effects of varicocelectomy on anti-sperm antibody in patients with varicocele
نویسندگان
چکیده
background: anti-sperm antibody (asa) can decrease sperm motility and, therefore, it is a cause of male infertility. the aim of this study was to evaluate the effects of varicocelectomy on anti-sperm antibody in patients with varicocele. methods: this observational study was conducted on 90 patients with varicocele at sina and imam khomeini hospitals during 2006 to 2009. all varicocelectomy candidates were selected for asa assessment both in semen and serum before and after surgery. asa level was measured using a direct method for semen and an indirect method of sperm mar test, for serum. paired t-test and mcnemar's test were used for data analysis, and p<0.05 was considered statistically significant. results: asa level in semen was 13.7% before, and 15.7% after three month of varicocelectomy (p=0.881). serum level of asa before and after surgery were 13.6% and 21.7%, respectively (p=0.033). three parameters including sperm count, motility and morphology showed recovery following, varicocelectomy, but only the difference in sperm motility was significant (p<0.05). conclusion: this study showed that varicocelectomy has no effect on semen asa. although serum antibody has been shown to increase after varicocelectomy but sperm motility will improve. varicocelectomy seems to have a beneficial effect on semen parameters in infertile men with varicocele.
منابع مشابه
Effects of Varicocelectomy on Anti-sperm Antibody in Patients with Varicocele
BACKGROUND Anti-sperm antibody (ASA) can decrease sperm motility and, therefore, it is a cause of male infertility. The aim of this study was to evaluate the effects of varicocelectomy on anti-sperm antibody in patients with varicocele. METHODS This observational study was conducted on 90 patients with varicocele at Sina and Imam Khomeini hospitals during 2006 to 2009. All varicocelectomy can...
متن کاملThe Effect of Varicocelectomy on the Spermogram of Patients with Subclinical Varicocele
This clinical study , carried out from 1996 to 1999, was aimed at assessing the effect of varicoceletomy on the spermogram of patients with subclinical varicocele. A total of 142 patients (mean age 28.1 ± 4.3) with varicocele (63 with subclinical) took part in the study. All individuals were informed and were satisfied to get involve in the study. Two spermograms were recorded one at the beginn...
متن کاملP-59: Effect of Microsurgical Varicocelectomy on Sperm Chromatin Packaging,Miscarriage and Pregnancy Rate in Infertile Men with Varicocele
Background: Although the pathophysiology of the testicular damage associated with varicocele remains unclear, but varicocelectomy is considered a suitable technique for the treatment of individuals with clinical varicocele. The current study was designed to assessed semen parameters, chromatin packaging, and pregnancy outcome before and after varicocelectomy. Materials and Methods: Semen sample...
متن کاملcomparison of the effects of varicocelectomy on the spermiogram of patients with subclinical versus clinical varicocele
many studies with different results have been conducted regarding varicocelectomy in patients with subclinical varicocele and its effect on semen parameters. this clinical trial was aimed at assessing the effect of varicocelectomy on the spermiogram of patients with subclinical varicocele. a total of 142 patients with varicocele (79 clinical and 63 subclinical) took part in the study. two sperm...
متن کاملEffects of Varicocelectomy on Serum Testosterone Levels among Infertile Men with Varicocele
Objective The main purpose of this study is to evaluate the effects of varicocelectomy on serum testosterone levels and semen quality in infertile men who suffer from varicocele. MaterialsAndMethods This prospective study enrolled 115 subjects with clinical varicocele grades II and III and 240 fertile men as the control group. Total volume of testosterone serum level (ng/dl) and semen quality w...
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عنوان ژورنال:
journal of reproduction and infertilityجلد ۱۴، شماره ۲، صفحات ۷۳-۷۹
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